University of Colorado | CU Anschutz Medical Campus

School of Medicine | Department of Pediatrics, Section of Neonatology

Official Title: Research Services Senior Laboratory Sciences Professional

Working Title: Senior Laboratory Science Professional

Position #00795051 - Requisition #25496

* Applications are accepted electronically ONLY at www.cu.edu/cu-careers *

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date. Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Denver: https://www.ucdenver.edu/coronavirus

Exemptions vary by campus location/department.

Campus/Unit-Specific Exemptions:

• Anschutz Campus - Exemptions are allowed for medical or religious reasons.
• Denver Campus - Exemptions are allowed for medical, religious, or personal reasons.
• Consolidated/Central Services Administration - Will follow Anschutz policy on exemptions.

The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

The University of Colorado Anschutz Medical Campus is a public education, clinical and research facility serving 4,500 students, and a world-class medical destination at the forefront of life-changing science, medicine, and healthcare. CU Anschutz offers more than 42 highly rated degree programs through 6 schools and colleges, and receives over $500 million in research awards each year. We are the single largest health professions education provider in Colorado, awarding nearly 1,450 degrees annually. Powered by our award-winning faculty, renowned researchers and a reputation for academic excellence, the CU Anschutz Medical Campus drives innovation from the classroom to the laboratory to the delivery of unparalleled patient care. Read CU Anschutz Quick Facts here.

The School of Medicine's Department of Pediatrics, Section of Neonatology has an opening for a full-time University Staff (unclassified) Senior Laboratory Science Professional position.

Jobs in the Research Services career family provide direct professional support of research activities. Functions include contracts and grants solicitation and administration, grant/agreement preparation, review and negotiation, regulatory compliance, sponsor communication and post and pre award management, human subject compliance, research animal management, research laboratory coordination and instruction, environmental health and safety, radiation control, hazardous materials use, disposal and training.

Senior Professionals are responsible for exercising discretion, analytical skill, personal accountability and responsibility in a wide range of areas including academic, administrative, managerial and student services functions. Work involves creating, integrating, applying and sharing knowledge directly related to a professional field. Work is performed fully independently.

Nature of Work

Senior Laboratory Science Professionals perform duties in an experimental lab, or wet lab, and handle a variety of chemicals and/or potential "wet" hazards. Senior Laboratory Science Professionals perform duties in laboratories where chemicals, drugs, or other materials or biological matters are tested and analyzed.

Some Assignments will not move beyond this level.

This professional will be working in a basic science lab that researches the neonatal innate immune response and key transcriptional signaling pathways activated after various clinically relevant exposures.

Applicants for this position must have a strong background in interrogating cell signaling pathways and the regulation of transcription factors. Technical experience with cell culture, cell and tissue processing, plasmid construction, transfection (over-expression plasmid, SiRNA, etc), ChIP, and primer design is required. The ideal candidate will be reliable, personable, highly motivated, and have demonstrated the ability to work independently when appropriate. This is an excellent opportunity to join a fast paced, productive research group. This position is located in the Perinatal Research Center on the Anschutz Medical Campus.

Examples of Duties Performed

• Collaborate with and support Principal Investigators (PI) and other stakeholders with laboratory and research functions
• Utilize a variety of laboratory techniques required for research projects
• Perform experiments and tabulate and analyze research
• Support analytical testing process using standard lab support knowledge in the collection and review of conditions, including preserving samples, completing sample preparation, documenting and communicating results
• Perform pre-analytical, analytical and post analytical test process and evaluate results produced
• Prepare lab for daily operations, including stocking materials, equipment, safety, cleanliness, and related areas
• Provide animal care related to research studies, as necessary
• Pick up, transport, and maintain results, samples, documents, materials and other items as needed
• Dispose of laboratory materials and samples using well established guidelines and instructions
• Review, complete and process logs, documents, databases, and related materials and information
• Provide support researching issues and developing recommendations to resolve process, unit and related issues
• Review and implement lab support policies, practices and programs to meet organizational, operations and management needs
• Ensure compliance with applicable laws, rules and regulations; receive guidance and direction or escalate when required
• Independently and creatively identify laboratory solutions
• Independently Review, develop and implement new or modified laboratory techniques required for research projects
• Assist Team Leads, Supervisors and/or management with creation and implementation of processes and procedures and quality improvement initiatives
• Assist and train junior team members
• Assist with developing or develop protocol-specific systems and documents including process flows, training manuals, and Standard Operating Procedures (SOPs) . Maintains subject level documentation and prepares documents, equipment and/or supplies
• Assist with identifying issues related to operational efficiency and shares results with leadership
• Provide laboratory science expertise and leadership in study design, study oversight, data management, data analysis and manuscript preparation to assist all levels of investigators, researchers and clinicians on new research activities across a wide range of disciplines
• Serve as a resource to PIs and other stakeholders

This description is a summary only and is describing the general level of work being performed, it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.

Salary and Benefits

The salary range (or hiring range) for this position has been established at $47,388 to $71,556.

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

This position is not eligible for overtime compensation.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits

Total Compensation Calculator: http://www.cu.edu/node/153125

Diversity and Equity

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@ucdenver.edu.

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

The University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Minimum Qualifications

• Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
  • A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
• Two (2) years professional level research experience

Required: Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications

• Master's degree or equivalent in Biology, Biochemistry, Chemistry, Animal Sciences or related field
• Three (3) years of experience in an experimental or wet laboratory
• Bachelor's degree in relevant field and 5 years of relevant experience
• Prior lab experience
• Familiar with RNA isolation, reverse transcription, and quantitative real-time PCR.
• Cell culture experience, including transfection
• Plasmid design and preparation, primer design and verification
• Chromatin immunoprecipitation (ChIP)

Competencies, Knowledge, Skills, and Abilities

• Able to handle and perform experiments using various murine models of human disease
• Strong experience in cell culture
• Able to construct and test expression plasmids, perform cell transfection
• Able to design primers and perform ChIP
• Must be willing to learn new techniques as needed, pay attention to detail, and work well in a lab with multiple investigators.
• Advanced knowledge of laboratory techniques including safety procedures and techniques
• Ability to communicate effectively, both in writing and orally
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
• Outstanding customer service skills
• Demonstrated commitment and leadership ability to advance diversity and inclusion
• Knowledge of basic human anatomy, physiology medical terminology
• Ability to interpret and master complex research protocol information
• This is an excellent opportunity to join a fast paced, productive research group.
• Word, Excel, Numbers, Dropbox, basic statistical analysis

Conditions of Employment

• Must successfully pass a 10-panel drug test through Children's Hospital Colorado
• Must be willing and able to pass a national criminal and sex-offender background check